whole genome sequencing Search Results


whole genome dna sequencing  (Broad Clinical Labs)
96
Broad Clinical Labs whole genome dna sequencing
Whole Genome Dna Sequencing, supplied by Broad Clinical Labs, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/whole+genome+sequencing/Whole+Genome+Sequencing/pm42013851-1110-4-17
Average 96 stars, based on 1 article reviews
whole genome dna sequencing - by Bioz Stars, 2026-09
96/100 stars
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mgieasy whole genome bisulfite library preparation kit  (Complete Genomics Inc)
97
Complete Genomics Inc mgieasy whole genome bisulfite library preparation kit
Genome‐wide DNA methylation analysis in WT and GM seeds before and after GO treatments. a) Circos plots show the methylation levels across different chromosomes for WT and GM seeds before and after GO exposure. The colored sections on the outer ring represent different chromosomes. The concentric rings from outer to inner illustrate untreated samples, 0.75 mg‐C/L GO‐treated samples, and 1.5 mg‐C/L GO‐treated <t>samples.</t> <t>Whole‐genome</t> methylation levels were calculated as mean values within 100 kb windows for each chromosome. The color gradient from cyan to red indicates the methylation percentages, whereas the innermost ring represents gene density. b) Whole‐genome methylation levels in CG, CHG, and CHH contexts for WT and GM seeds after various GO exposures (sample size n = 3). Data are presented as means ± SD, with gray and red dots depicting individual data points in the WT and GM groups. Three biological replicates were included for each treatment. Independent sample two‐sided t ‐tests were performed: * indicates significant differences within the same genotype relative to the condition without GO, and # indicates significant differences between GM and WT under the same treatment. Significant differences are marked with p values. c) Differential methylation regions at promoter regions and gene bodies of key genes (Figure ) are represented by a color gradient showing Log 2 FC in methylation levels. Triangles and circles indicate CG and CHH methylation, respectively. No differential methylation was observed in the CHG context. Regions without differential methylation are blank. d) Dot plots of differential methylation for ALA metabolism‐related genes compare promoter and gene body methylation across conditions. Blue and red dots denote different comparisons, as indicated in the legend. Dots with circles indicate methylation levels with |Log 2 FC| >10.
Mgieasy Whole Genome Bisulfite Library Preparation Kit, supplied by Complete Genomics Inc, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/whole+genome+sequencing/MGIEasy+Whole+Genome+Methylation+Sequencing+Library+Prep+Kit+V3%2E0/pmc12407378-262-6-12
Average 97 stars, based on 1 article reviews
mgieasy whole genome bisulfite library preparation kit - by Bioz Stars, 2026-09
97/100 stars
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sophia whole exome solution kit  (Sophia Genetics)
97
Sophia Genetics sophia whole exome solution kit
Genome‐wide DNA methylation analysis in WT and GM seeds before and after GO treatments. a) Circos plots show the methylation levels across different chromosomes for WT and GM seeds before and after GO exposure. The colored sections on the outer ring represent different chromosomes. The concentric rings from outer to inner illustrate untreated samples, 0.75 mg‐C/L GO‐treated samples, and 1.5 mg‐C/L GO‐treated <t>samples.</t> <t>Whole‐genome</t> methylation levels were calculated as mean values within 100 kb windows for each chromosome. The color gradient from cyan to red indicates the methylation percentages, whereas the innermost ring represents gene density. b) Whole‐genome methylation levels in CG, CHG, and CHH contexts for WT and GM seeds after various GO exposures (sample size n = 3). Data are presented as means ± SD, with gray and red dots depicting individual data points in the WT and GM groups. Three biological replicates were included for each treatment. Independent sample two‐sided t ‐tests were performed: * indicates significant differences within the same genotype relative to the condition without GO, and # indicates significant differences between GM and WT under the same treatment. Significant differences are marked with p values. c) Differential methylation regions at promoter regions and gene bodies of key genes (Figure ) are represented by a color gradient showing Log 2 FC in methylation levels. Triangles and circles indicate CG and CHH methylation, respectively. No differential methylation was observed in the CHG context. Regions without differential methylation are blank. d) Dot plots of differential methylation for ALA metabolism‐related genes compare promoter and gene body methylation across conditions. Blue and red dots denote different comparisons, as indicated in the legend. Dots with circles indicate methylation levels with |Log 2 FC| >10.
Sophia Whole Exome Solution Kit, supplied by Sophia Genetics, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/whole+genome+sequencing/Rare+disorders/pm37965175-70-10-15
Average 97 stars, based on 1 article reviews
sophia whole exome solution kit - by Bioz Stars, 2026-09
97/100 stars
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alamut visual version 2 15  (Sophia Genetics)
97
Sophia Genetics alamut visual version 2 15
Genome‐wide DNA methylation analysis in WT and GM seeds before and after GO treatments. a) Circos plots show the methylation levels across different chromosomes for WT and GM seeds before and after GO exposure. The colored sections on the outer ring represent different chromosomes. The concentric rings from outer to inner illustrate untreated samples, 0.75 mg‐C/L GO‐treated samples, and 1.5 mg‐C/L GO‐treated <t>samples.</t> <t>Whole‐genome</t> methylation levels were calculated as mean values within 100 kb windows for each chromosome. The color gradient from cyan to red indicates the methylation percentages, whereas the innermost ring represents gene density. b) Whole‐genome methylation levels in CG, CHG, and CHH contexts for WT and GM seeds after various GO exposures (sample size n = 3). Data are presented as means ± SD, with gray and red dots depicting individual data points in the WT and GM groups. Three biological replicates were included for each treatment. Independent sample two‐sided t ‐tests were performed: * indicates significant differences within the same genotype relative to the condition without GO, and # indicates significant differences between GM and WT under the same treatment. Significant differences are marked with p values. c) Differential methylation regions at promoter regions and gene bodies of key genes (Figure ) are represented by a color gradient showing Log 2 FC in methylation levels. Triangles and circles indicate CG and CHH methylation, respectively. No differential methylation was observed in the CHG context. Regions without differential methylation are blank. d) Dot plots of differential methylation for ALA metabolism‐related genes compare promoter and gene body methylation across conditions. Blue and red dots denote different comparisons, as indicated in the legend. Dots with circles indicate methylation levels with |Log 2 FC| >10.
Alamut Visual Version 2 15, supplied by Sophia Genetics, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/whole+genome+sequencing/Alamut+Visual+Plus/pmc12215293-105-0-5
Average 97 stars, based on 1 article reviews
alamut visual version 2 15 - by Bioz Stars, 2026-09
97/100 stars
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sophia hereditary cancer solutiontm hcs v1 1  (Sophia Genetics)
97
Sophia Genetics sophia hereditary cancer solutiontm hcs v1 1
Genome‐wide DNA methylation analysis in WT and GM seeds before and after GO treatments. a) Circos plots show the methylation levels across different chromosomes for WT and GM seeds before and after GO exposure. The colored sections on the outer ring represent different chromosomes. The concentric rings from outer to inner illustrate untreated samples, 0.75 mg‐C/L GO‐treated samples, and 1.5 mg‐C/L GO‐treated <t>samples.</t> <t>Whole‐genome</t> methylation levels were calculated as mean values within 100 kb windows for each chromosome. The color gradient from cyan to red indicates the methylation percentages, whereas the innermost ring represents gene density. b) Whole‐genome methylation levels in CG, CHG, and CHH contexts for WT and GM seeds after various GO exposures (sample size n = 3). Data are presented as means ± SD, with gray and red dots depicting individual data points in the WT and GM groups. Three biological replicates were included for each treatment. Independent sample two‐sided t ‐tests were performed: * indicates significant differences within the same genotype relative to the condition without GO, and # indicates significant differences between GM and WT under the same treatment. Significant differences are marked with p values. c) Differential methylation regions at promoter regions and gene bodies of key genes (Figure ) are represented by a color gradient showing Log 2 FC in methylation levels. Triangles and circles indicate CG and CHH methylation, respectively. No differential methylation was observed in the CHG context. Regions without differential methylation are blank. d) Dot plots of differential methylation for ALA metabolism‐related genes compare promoter and gene body methylation across conditions. Blue and red dots denote different comparisons, as indicated in the legend. Dots with circles indicate methylation levels with |Log 2 FC| >10.
Sophia Hereditary Cancer Solutiontm Hcs V1 1, supplied by Sophia Genetics, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/whole+genome+sequencing/Hereditary+cancers/pm40596117-106-15-22
Average 97 stars, based on 1 article reviews
sophia hereditary cancer solutiontm hcs v1 1 - by Bioz Stars, 2026-09
97/100 stars
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high output microbial whole genome sequencing  (Broad Clinical Labs)
94
Broad Clinical Labs high output microbial whole genome sequencing
Genome‐wide DNA methylation analysis in WT and GM seeds before and after GO treatments. a) Circos plots show the methylation levels across different chromosomes for WT and GM seeds before and after GO exposure. The colored sections on the outer ring represent different chromosomes. The concentric rings from outer to inner illustrate untreated samples, 0.75 mg‐C/L GO‐treated samples, and 1.5 mg‐C/L GO‐treated <t>samples.</t> <t>Whole‐genome</t> methylation levels were calculated as mean values within 100 kb windows for each chromosome. The color gradient from cyan to red indicates the methylation percentages, whereas the innermost ring represents gene density. b) Whole‐genome methylation levels in CG, CHG, and CHH contexts for WT and GM seeds after various GO exposures (sample size n = 3). Data are presented as means ± SD, with gray and red dots depicting individual data points in the WT and GM groups. Three biological replicates were included for each treatment. Independent sample two‐sided t ‐tests were performed: * indicates significant differences within the same genotype relative to the condition without GO, and # indicates significant differences between GM and WT under the same treatment. Significant differences are marked with p values. c) Differential methylation regions at promoter regions and gene bodies of key genes (Figure ) are represented by a color gradient showing Log 2 FC in methylation levels. Triangles and circles indicate CG and CHH methylation, respectively. No differential methylation was observed in the CHG context. Regions without differential methylation are blank. d) Dot plots of differential methylation for ALA metabolism‐related genes compare promoter and gene body methylation across conditions. Blue and red dots denote different comparisons, as indicated in the legend. Dots with circles indicate methylation levels with |Log 2 FC| >10.
High Output Microbial Whole Genome Sequencing, supplied by Broad Clinical Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/whole+genome+sequencing/Microbial+Whole+Genome+Sequencing/pmc11059386-241-2-12
Average 94 stars, based on 1 article reviews
high output microbial whole genome sequencing - by Bioz Stars, 2026-09
94/100 stars
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whole genome sequences fragaria vesca  (Lindl GmbH)
90
Lindl GmbH whole genome sequences fragaria vesca
Genome‐wide DNA methylation analysis in WT and GM seeds before and after GO treatments. a) Circos plots show the methylation levels across different chromosomes for WT and GM seeds before and after GO exposure. The colored sections on the outer ring represent different chromosomes. The concentric rings from outer to inner illustrate untreated samples, 0.75 mg‐C/L GO‐treated samples, and 1.5 mg‐C/L GO‐treated <t>samples.</t> <t>Whole‐genome</t> methylation levels were calculated as mean values within 100 kb windows for each chromosome. The color gradient from cyan to red indicates the methylation percentages, whereas the innermost ring represents gene density. b) Whole‐genome methylation levels in CG, CHG, and CHH contexts for WT and GM seeds after various GO exposures (sample size n = 3). Data are presented as means ± SD, with gray and red dots depicting individual data points in the WT and GM groups. Three biological replicates were included for each treatment. Independent sample two‐sided t ‐tests were performed: * indicates significant differences within the same genotype relative to the condition without GO, and # indicates significant differences between GM and WT under the same treatment. Significant differences are marked with p values. c) Differential methylation regions at promoter regions and gene bodies of key genes (Figure ) are represented by a color gradient showing Log 2 FC in methylation levels. Triangles and circles indicate CG and CHH methylation, respectively. No differential methylation was observed in the CHG context. Regions without differential methylation are blank. d) Dot plots of differential methylation for ALA metabolism‐related genes compare promoter and gene body methylation across conditions. Blue and red dots denote different comparisons, as indicated in the legend. Dots with circles indicate methylation levels with |Log 2 FC| >10.
Whole Genome Sequences Fragaria Vesca, supplied by Lindl GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/whole+genome+sequencing/whole+genome+sequences+fragaria+vesca/10__1016_slash_j__pld__2022__04__003-56-6-8
Average 90 stars, based on 1 article reviews
whole genome sequences fragaria vesca - by Bioz Stars, 2026-09
90/100 stars
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shallow whole genome sequencing  (Broad Institute Inc)
90
Broad Institute Inc shallow whole genome sequencing
Genome‐wide DNA methylation analysis in WT and GM seeds before and after GO treatments. a) Circos plots show the methylation levels across different chromosomes for WT and GM seeds before and after GO exposure. The colored sections on the outer ring represent different chromosomes. The concentric rings from outer to inner illustrate untreated samples, 0.75 mg‐C/L GO‐treated samples, and 1.5 mg‐C/L GO‐treated <t>samples.</t> <t>Whole‐genome</t> methylation levels were calculated as mean values within 100 kb windows for each chromosome. The color gradient from cyan to red indicates the methylation percentages, whereas the innermost ring represents gene density. b) Whole‐genome methylation levels in CG, CHG, and CHH contexts for WT and GM seeds after various GO exposures (sample size n = 3). Data are presented as means ± SD, with gray and red dots depicting individual data points in the WT and GM groups. Three biological replicates were included for each treatment. Independent sample two‐sided t ‐tests were performed: * indicates significant differences within the same genotype relative to the condition without GO, and # indicates significant differences between GM and WT under the same treatment. Significant differences are marked with p values. c) Differential methylation regions at promoter regions and gene bodies of key genes (Figure ) are represented by a color gradient showing Log 2 FC in methylation levels. Triangles and circles indicate CG and CHH methylation, respectively. No differential methylation was observed in the CHG context. Regions without differential methylation are blank. d) Dot plots of differential methylation for ALA metabolism‐related genes compare promoter and gene body methylation across conditions. Blue and red dots denote different comparisons, as indicated in the legend. Dots with circles indicate methylation levels with |Log 2 FC| >10.
Shallow Whole Genome Sequencing, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/whole+genome+sequencing/shallow+whole+genome+sequencing/pmc11998630-9-6-14
Average 90 stars, based on 1 article reviews
shallow whole genome sequencing - by Bioz Stars, 2026-09
90/100 stars
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rapid whole genome sequencing  (Intermountain Precision Genomics)
90
Intermountain Precision Genomics rapid whole genome sequencing
Genome‐wide DNA methylation analysis in WT and GM seeds before and after GO treatments. a) Circos plots show the methylation levels across different chromosomes for WT and GM seeds before and after GO exposure. The colored sections on the outer ring represent different chromosomes. The concentric rings from outer to inner illustrate untreated samples, 0.75 mg‐C/L GO‐treated samples, and 1.5 mg‐C/L GO‐treated <t>samples.</t> <t>Whole‐genome</t> methylation levels were calculated as mean values within 100 kb windows for each chromosome. The color gradient from cyan to red indicates the methylation percentages, whereas the innermost ring represents gene density. b) Whole‐genome methylation levels in CG, CHG, and CHH contexts for WT and GM seeds after various GO exposures (sample size n = 3). Data are presented as means ± SD, with gray and red dots depicting individual data points in the WT and GM groups. Three biological replicates were included for each treatment. Independent sample two‐sided t ‐tests were performed: * indicates significant differences within the same genotype relative to the condition without GO, and # indicates significant differences between GM and WT under the same treatment. Significant differences are marked with p values. c) Differential methylation regions at promoter regions and gene bodies of key genes (Figure ) are represented by a color gradient showing Log 2 FC in methylation levels. Triangles and circles indicate CG and CHH methylation, respectively. No differential methylation was observed in the CHG context. Regions without differential methylation are blank. d) Dot plots of differential methylation for ALA metabolism‐related genes compare promoter and gene body methylation across conditions. Blue and red dots denote different comparisons, as indicated in the legend. Dots with circles indicate methylation levels with |Log 2 FC| >10.
Rapid Whole Genome Sequencing, supplied by Intermountain Precision Genomics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/whole+genome+sequencing/rapid+whole+genome+sequencing/10__1212_slash_wnl__0000000000011891-80-17-11
Average 90 stars, based on 1 article reviews
rapid whole genome sequencing - by Bioz Stars, 2026-09
90/100 stars
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complete gene sequencing  (Johns Hopkins HealthCare)
90
Johns Hopkins HealthCare complete gene sequencing
Genome‐wide DNA methylation analysis in WT and GM seeds before and after GO treatments. a) Circos plots show the methylation levels across different chromosomes for WT and GM seeds before and after GO exposure. The colored sections on the outer ring represent different chromosomes. The concentric rings from outer to inner illustrate untreated samples, 0.75 mg‐C/L GO‐treated samples, and 1.5 mg‐C/L GO‐treated <t>samples.</t> <t>Whole‐genome</t> methylation levels were calculated as mean values within 100 kb windows for each chromosome. The color gradient from cyan to red indicates the methylation percentages, whereas the innermost ring represents gene density. b) Whole‐genome methylation levels in CG, CHG, and CHH contexts for WT and GM seeds after various GO exposures (sample size n = 3). Data are presented as means ± SD, with gray and red dots depicting individual data points in the WT and GM groups. Three biological replicates were included for each treatment. Independent sample two‐sided t ‐tests were performed: * indicates significant differences within the same genotype relative to the condition without GO, and # indicates significant differences between GM and WT under the same treatment. Significant differences are marked with p values. c) Differential methylation regions at promoter regions and gene bodies of key genes (Figure ) are represented by a color gradient showing Log 2 FC in methylation levels. Triangles and circles indicate CG and CHH methylation, respectively. No differential methylation was observed in the CHG context. Regions without differential methylation are blank. d) Dot plots of differential methylation for ALA metabolism‐related genes compare promoter and gene body methylation across conditions. Blue and red dots denote different comparisons, as indicated in the legend. Dots with circles indicate methylation levels with |Log 2 FC| >10.
Complete Gene Sequencing, supplied by Johns Hopkins HealthCare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/whole+genome+sequencing/whole+genome+sequencing/pmc03198785-40-23-28
Average 90 stars, based on 1 article reviews
complete gene sequencing - by Bioz Stars, 2026-09
90/100 stars
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artic sars-cov-2 ont sequencing protocol  (Oxford Nanopore)
90
Oxford Nanopore artic sars-cov-2 ont sequencing protocol
Genome‐wide DNA methylation analysis in WT and GM seeds before and after GO treatments. a) Circos plots show the methylation levels across different chromosomes for WT and GM seeds before and after GO exposure. The colored sections on the outer ring represent different chromosomes. The concentric rings from outer to inner illustrate untreated samples, 0.75 mg‐C/L GO‐treated samples, and 1.5 mg‐C/L GO‐treated <t>samples.</t> <t>Whole‐genome</t> methylation levels were calculated as mean values within 100 kb windows for each chromosome. The color gradient from cyan to red indicates the methylation percentages, whereas the innermost ring represents gene density. b) Whole‐genome methylation levels in CG, CHG, and CHH contexts for WT and GM seeds after various GO exposures (sample size n = 3). Data are presented as means ± SD, with gray and red dots depicting individual data points in the WT and GM groups. Three biological replicates were included for each treatment. Independent sample two‐sided t ‐tests were performed: * indicates significant differences within the same genotype relative to the condition without GO, and # indicates significant differences between GM and WT under the same treatment. Significant differences are marked with p values. c) Differential methylation regions at promoter regions and gene bodies of key genes (Figure ) are represented by a color gradient showing Log 2 FC in methylation levels. Triangles and circles indicate CG and CHH methylation, respectively. No differential methylation was observed in the CHG context. Regions without differential methylation are blank. d) Dot plots of differential methylation for ALA metabolism‐related genes compare promoter and gene body methylation across conditions. Blue and red dots denote different comparisons, as indicated in the legend. Dots with circles indicate methylation levels with |Log 2 FC| >10.
Artic Sars Cov 2 Ont Sequencing Protocol, supplied by Oxford Nanopore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/whole+genome+sequencing/sars+cov+2+whole+genome+sequencing/pm35365787-141-8-11
Average 90 stars, based on 1 article reviews
artic sars-cov-2 ont sequencing protocol - by Bioz Stars, 2026-09
90/100 stars
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whole-genome sequencing  (Microsynth ag)
90
Microsynth ag whole-genome sequencing
Genome‐wide DNA methylation analysis in WT and GM seeds before and after GO treatments. a) Circos plots show the methylation levels across different chromosomes for WT and GM seeds before and after GO exposure. The colored sections on the outer ring represent different chromosomes. The concentric rings from outer to inner illustrate untreated samples, 0.75 mg‐C/L GO‐treated samples, and 1.5 mg‐C/L GO‐treated <t>samples.</t> <t>Whole‐genome</t> methylation levels were calculated as mean values within 100 kb windows for each chromosome. The color gradient from cyan to red indicates the methylation percentages, whereas the innermost ring represents gene density. b) Whole‐genome methylation levels in CG, CHG, and CHH contexts for WT and GM seeds after various GO exposures (sample size n = 3). Data are presented as means ± SD, with gray and red dots depicting individual data points in the WT and GM groups. Three biological replicates were included for each treatment. Independent sample two‐sided t ‐tests were performed: * indicates significant differences within the same genotype relative to the condition without GO, and # indicates significant differences between GM and WT under the same treatment. Significant differences are marked with p values. c) Differential methylation regions at promoter regions and gene bodies of key genes (Figure ) are represented by a color gradient showing Log 2 FC in methylation levels. Triangles and circles indicate CG and CHH methylation, respectively. No differential methylation was observed in the CHG context. Regions without differential methylation are blank. d) Dot plots of differential methylation for ALA metabolism‐related genes compare promoter and gene body methylation across conditions. Blue and red dots denote different comparisons, as indicated in the legend. Dots with circles indicate methylation levels with |Log 2 FC| >10.
Whole Genome Sequencing, supplied by Microsynth ag, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/whole+genome+sequencing/whole+genome+sequencing/pmc09257628-151-0-23
Average 90 stars, based on 1 article reviews
whole-genome sequencing - by Bioz Stars, 2026-09
90/100 stars
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Image Search Results


Genome‐wide DNA methylation analysis in WT and GM seeds before and after GO treatments. a) Circos plots show the methylation levels across different chromosomes for WT and GM seeds before and after GO exposure. The colored sections on the outer ring represent different chromosomes. The concentric rings from outer to inner illustrate untreated samples, 0.75 mg‐C/L GO‐treated samples, and 1.5 mg‐C/L GO‐treated samples. Whole‐genome methylation levels were calculated as mean values within 100 kb windows for each chromosome. The color gradient from cyan to red indicates the methylation percentages, whereas the innermost ring represents gene density. b) Whole‐genome methylation levels in CG, CHG, and CHH contexts for WT and GM seeds after various GO exposures (sample size n = 3). Data are presented as means ± SD, with gray and red dots depicting individual data points in the WT and GM groups. Three biological replicates were included for each treatment. Independent sample two‐sided t ‐tests were performed: * indicates significant differences within the same genotype relative to the condition without GO, and # indicates significant differences between GM and WT under the same treatment. Significant differences are marked with p values. c) Differential methylation regions at promoter regions and gene bodies of key genes (Figure ) are represented by a color gradient showing Log 2 FC in methylation levels. Triangles and circles indicate CG and CHH methylation, respectively. No differential methylation was observed in the CHG context. Regions without differential methylation are blank. d) Dot plots of differential methylation for ALA metabolism‐related genes compare promoter and gene body methylation across conditions. Blue and red dots denote different comparisons, as indicated in the legend. Dots with circles indicate methylation levels with |Log 2 FC| >10.

Journal: Advanced Science

Article Title: Accounting for ALA Natural Mutations Enhances the Efficiency of Graphene Oxide Nanopriming in Bar ‐Modified Arabidopsis

doi: 10.1002/advs.202500058

Figure Lengend Snippet: Genome‐wide DNA methylation analysis in WT and GM seeds before and after GO treatments. a) Circos plots show the methylation levels across different chromosomes for WT and GM seeds before and after GO exposure. The colored sections on the outer ring represent different chromosomes. The concentric rings from outer to inner illustrate untreated samples, 0.75 mg‐C/L GO‐treated samples, and 1.5 mg‐C/L GO‐treated samples. Whole‐genome methylation levels were calculated as mean values within 100 kb windows for each chromosome. The color gradient from cyan to red indicates the methylation percentages, whereas the innermost ring represents gene density. b) Whole‐genome methylation levels in CG, CHG, and CHH contexts for WT and GM seeds after various GO exposures (sample size n = 3). Data are presented as means ± SD, with gray and red dots depicting individual data points in the WT and GM groups. Three biological replicates were included for each treatment. Independent sample two‐sided t ‐tests were performed: * indicates significant differences within the same genotype relative to the condition without GO, and # indicates significant differences between GM and WT under the same treatment. Significant differences are marked with p values. c) Differential methylation regions at promoter regions and gene bodies of key genes (Figure ) are represented by a color gradient showing Log 2 FC in methylation levels. Triangles and circles indicate CG and CHH methylation, respectively. No differential methylation was observed in the CHG context. Regions without differential methylation are blank. d) Dot plots of differential methylation for ALA metabolism‐related genes compare promoter and gene body methylation across conditions. Blue and red dots denote different comparisons, as indicated in the legend. Dots with circles indicate methylation levels with |Log 2 FC| >10.

Article Snippet: Library construction was performed using an MGIEasy whole‐genome bisulfite library preparation kit (MGI).

Techniques: Genome Wide, DNA Methylation Assay, Methylation